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Food additives — nitrates and nitrites, MSG, artificial sweeteners, and sulfites — are a chemically diverse category of migraine triggers, each with its own mechanism and evidence base. Condiments, Additives, and Migraine covers each compound in depth, including which have well-established mechanisms and which have much weaker evidence than their popular reputation suggests.
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Lipton RB, Newman LC, Cohen JS, Solomon S. Aspartame as a dietary trigger of headache. Headache. 1989.
How falling blood glucose activates the stress axis and trigeminovascular system, reactive hypoglycemia, why meal timing matters as much as content, and practical meal planning.
The one to two percent body weight threshold, why thirst is a late indicator, mechanisms including cerebral vasodilation and magnesium depletion, rapid dehydration situations, and rehydration strategies.
Cortical hyperexcitability and failed habituation, visual complexity triggers, auditory hypersensitivity, practical sensory management strategies, and planning around high-stimulation environments.
Hypoxia-driven cerebral vasodilation, hypocapnia and oscillating vascular changes, altitude sickness and migraine overlap, barometric pressure at altitude, and acetazolamide for prevention.
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